This monograph discusses challenges faced during the implementation of national eHealth programs. In particular, it analyzes the causes of stakeholders´ reluctance to adopt these technologies by drawing on user resistance theory and context specific variables. Taking the example of the introduction of the electronic health card (Elektronische Gesundheitskarte - eGK) technology in Germany, the book presents insights into why these programs are often lengthy, costly and have previously been met with fierce resistance from key stakeholders. It also presents a quantitative and qualitative study of individual physicians' resistance behavior towards these new eHealth technologies.