This book presents industrial problems to mathematicians, including the mathematical formulation of the problems. The first twenty chapters of the book include the industrial background, relevant mathematical literature, a list of open mathematical problems and, in some cases, reference to a solution or a partial solution of the problem. Most of the problems, however, are still open and they are addressed to mathematicians. The last chapter of the book contains reference to solutions of problems presented in the previous volume of Mathematics in Industrial Problems, Part 3 published in the IMA series, as volume 31. The topics of the book include semiconductor devices and processing; particles dynamics; polymer chains and electrophoresis; catalytic converter, robotics and CFD in the automobile industry, superconductivity, magnetic storage devices, signal processing, and experimental design. The book will be of interest to mathematicians seeking to work on mathematical problems which arise in industry. It will also be of interest to mathematicians and scientists who would like to learn about the interaction between mathematics and industry, what type of problems arise, how they are modeled, etc. Scientists working in industry may also be interested in the book as they discover that some of the topics dealt with are connected to their own work.